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And with Retatrutide, that baseline is incredibly high

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For many people, poor eating habits and insufficient exercise place them in a seemingly perpetual fat storage mode, making it difficult to lose weight and shed unwanted inches

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The STEP 4 study [93] had a cross-over design, where at 20 weeks a new randomization took place where participants from the original SMG group were randomly selected (in a 2:1 ratio) to continue with SMG or receive placebo and followed for a further 48 weeks

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