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MT-2s cyclic structure confers significantly enhanced resistance to enzymatic degradation, with an effective research half-life of approximately one to two hours, providing a substantially wider in vitro and pre-clinical experimental window than the endogenous compound

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Since smoking was known to be associated with ferroptosis and GPX4 expression 29 , we believed that the association between smoking and LUSC may be one of the potential reasons why no correlation could be observed between GPX4 expression and LUSC in this study

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