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New @Nature A quintuple [GLP-1 + 4 other] receptor agonist drug that exceeds effects of the dual receptor (GLP-1 and GIP, tirzepatide) in the experimental model vs diabetes and obesity (in case you thought a dual receptor was max effect, as also seen with retatrutide, a triple receptor agonist) nature.com/articles/s4158 New @Nature A quintuple [GLP-1 + 4 other] receptor agonist drug that exceeds effects of the dual receptor (GLP-1 and GIP, tirzepatide) in the experimental model vs diabetes and obesity (in case you thought a dual receptor was max effect, as also seen with retatrutide, a triple receptor agonist) nature.com/articles/s4158 A different quintuple receptor agonist will be presented at ADA (GLP-1/GIP/glucagon/amylin/calcitonin) if it is designed to be quintuple agonist, I wonder how many more it hits off-target

It is made from three amino acids, cysteine, glycine, and glutamic acid

Prolonged glucagon infusion does not affect energy expenditure in individuals with overweight/obesity: a randomized trial

The MIVM Cocktail and Hangover IV contain a high dose of glutathione and other supplements to help you recover

Hypoglycaemia risk with Rybelsus alone is low but may increase with a double dose, particularly in patients taking sulphonylureas or insulin concurrently

When it is suppressed, as it typically is during caloric restriction, muscle breakdown accelerates