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En modelos animales preclnicos, dado su carcter de molcula pequea oral-activa, los diseos han contemplado dosificacin por va oral o intraperitoneal segn el protocolo aprobado por el comit de tica institucional, con esquemas de administracin diaria y ventanas de tratamiento que abarcan varias semanas para observar efectos sobre composicin corporal

Blunted lipolytic response to fasting in abdominally obese women: evidence for involvement of hyposomatotropism

52 Koyama, K., Usami, T., Takeuchi, O., Morozumi, K