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Increased levels of TFAs may also contribute to the pathogenesis of mental disorders as a result of altering the neuronal lipid membrane composition, leading to reduced levels of polyunsaturated fatty acid content, reduced membrane fluidity, and impaired neurotransmission (28, 30, 31)

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Differential activity of lipoic acid enantiomers in cell culture

Diabetes alters the expression profiles of numerous non-coding RNAs in sperm, especially miRNAs, which may influence spermatogenesis and fertility [199]

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