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Specific examples of methylation in detoxification: Arsenic detoxification requires sequential methylation: arsenite to monomethylarsonic acid to dimethylarsinic acid (the excretable form), catalyzed by arsenic methyltransferase (AS3MT) using SAM-e R Mercury undergoes methylation by gut bacteria, converting inorganic mercury to more toxic methylmercury (this is detrimental methylation, not detoxification) R COMT methylation of 4-hydroxy catechol estrogens prevents them from forming reactive quinones that generate ROS and DNA damage R 6

Reconstituted peptides should always be refrigerated, not frozen

Can I add the peptides epitalon or deltasleepinducing peptide (DSIP) to my current regimenincluding nebivolol 2.5 mg, Ltryptophan, Ltheanine, lemborexant, ibuprofen, pyridostigmine, and baclofento improve sleep?

For optimum results, drink a 1/3 of a bottle 30 minutes to one hour before exercise and/or between meals

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