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Based on the observation that a large proportion of lean tissues lost during weight loss seems to be from our adipose tissue, and the proportion of total lean mass increased after weight loss in STEP 1 and SUSTAIN 8 trials, its unlikely that using semaglutide to support weight loss leads to clinically meaningful reductions in muscle and other lean tissues
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(J Appl Physiol 2011) showed BPC-157 accelerates tendon fibroblast migration in vitro via FAK and paxillin phosphorylation, a critical pathway in focal adhesion remodeling
Reprod Biol Endocrinol 16 , 5 (2018)
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