Glutathione plays a crucial role in several cellular and biochemical functions, including protecting cells from free radicals or detoxifying the body through the liver, as glutathione is present in every cell in the body, particularly in high concentrations in the liver
Importantly, p53-mediated ferroptosis can also occur independently of the canonical SLC7A11GSHGPX4 axis through a distinct p53SAT1ALOX15 pathway
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PMID 15830915
Nie L-J, Liang J, Shan F, et al
Low, intermittent exposure may drive normal repair, and high, continuous exposure could result in fibrosis or undesired overgrowth