REDD1 functions at the crossroads between the therapeutic and adverse effects of topical glucocorticoids
"Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis." Proc Natl Acad Sci
It also helps "re-up" other antioxidants like Vitamin E
Abstract The World Health Organization (WHO) has identified type 2 diabetes (T2DM) as a neglected, important, and re-emerging risk factor for tuberculosis (TB), especially in low and middle-income countries where TB is endemic

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