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Abbreviations GLP-1: glucagon-like peptide 1 GIP: glucose-dependent insulinotropic polypeptide [Ca 2+ ] i : intracellular Ca 2+ concentrations Adcy: adenylate cyclase CICR: Ca 2+ -induced Ca 2+ release T2D: type 2 diabetes mellitus NOTES

Safety & Possible Side Effects B12 injections are generally very safe and well-tolerated

Pharmacological agents under investigation for the treatment of COVID-19 can affect glucose metabolism, particularly in patients with diabetes mellitus

Gastrointestinal tolerance requires careful tracking, as nausea, vomiting, diarrhea, and constipation represent the most common adverse effects

Psychopharmacology (Berl) 60: 137-146

A federal judge in Texas has rejected a bid by compounding pharmacies to allow them to continue making copies of Novo Nordisk's blockbuster drugs Ozempic and Wegovy, upholding the U.S