In addition, we observed that individuals who had a redeemed prescription for GLP-1a had mean higher baseline HbA 1c values measured closest to the index date, potentially underestimating the risk of major CI for DPP4-i, rather than overestimating it
In addition, the available data only included diagnoses based on clinical admissions for major and mild CI, often established in outpatient clinics
Cole SR, Hernan MA (2008) Constructing inverse probability weights for marginal structural models
Pharmacoepidemiol Drug Saf 31:5560
It is important to note that in UK coding practice, codes from the T36-T50 range are reserved for poisoning (overdose, wrong substance given or taken in error, or wrong route of administration) and should not be used for adverse effects occurring during correct therapeutic use
BMI codes and other categories of Z codes (Z68, Z86.3 etc.) may be used as a secondary code when the associated diagnosis is documented. A BMI reported by a nutritionist or registered nurse may be used if the diagnosis of obesity, overweight, or underweight is documented by the responsible physician