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Increased TMAO levels in addition to endothelial dysfunction, vascular aging, and oxidative stresses have been shown to cause thrombotic events and platelet excitability in humans, which in turn induce atherosclerosis [69, 72]

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There's no established "ideal" percentage yet but 1-2% is the evidence-backed range

Oxidative medicine and cellular longevity, 2013, 972913

What this means is that although L-carnitine supplementation may help optimise carnitine metabolism and fat oxidation, its not going to be a stand-alone solution for losing weight

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