Approximately 57% of patients experienced decrease in appetite, which was consistent across the PIONEER trials [35,36,37,38,39,40,41,42,43,44]
95% CI, 0.35 to 3.14)
10.1016/j.metabol.2013.09.009 Metabolism Summary Keywords T2DM (type 2 diabetes), GLP-1, -cell, PARP-1, ABCA1 Citation Li R, Sun X, Li P, Li W, Zhao L, Zhu L and Zhu S (2021) GLP-1-Induced AMPK Activation Inhibits PARP-1 and Promotes LXR-Mediated ABCA1 Expression to Protect Pancreatic -Cells Against Cholesterol-Induced Toxicity Through Cholesterol Efflux
Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial
Prioritize lean protein sources like low-fat Greek yogurt, eggs, chicken, tuna, tofu, lentils and beans at every meal and snack to help maintain muscle mass and support healthy digestion
Cagrilintide, survodutide, and orforglipron are all in the pipeline