Supports collagen synthesis, skin repair & tissue remodeling
D P Jones, R J Coates, E W Flagg, J W Eley, G Block, R S Greenberg, E W Gunter, B Jackson - Glutathione in foods listed in the National Cancer Institute's Health Habits and History Food Frequency Questionnaire - Nutr Cancer - 1992
Simple notes about subjective experience, objective measurements, and any concerns enable informed decisions about continuing, adjusting, or discontinuing individual components
Therefore, the ratio of GSH and GSSG has been noted as index of oxidative stress
This creates feed-forward cycles that exacerbate cuproptosis: mtROS oxidize cytosolic GSH, releasing bound Cu, and may upregulate the copper importer CTR1 via pathways such as NF-B, increasing copper influx [65]
Vitamin E (800 IU daily) has some evidence supporting its use in non-diabetic adults with biopsy-proven NASH, but this is specialist-initiated, off-label use requiring discussion of potential risks, including increased risk of haemorrhagic stroke and prostate cancer with long-term use