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Participants in the study all had pre-existing cardiovascular disease: a previous heart attack, stroke or symptomatic peripheral arterial disease and a BMI over 27

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Joint pain is not a direct side effect of the medication, but rapid weight loss can change your posture and gait, which may temporarily stress your joints

The side effects typically subside as the patient gets used to taking the medication and their body adjusts to the dosage

Repeated injection at the same site causes lipohypertrophythickened, hardened fat tissue that reduces medication absorption and increases injection pain

For patients experiencing acid reflux symptoms while taking Zepbound, several evidence-based management strategies can provide relief without necessarily requiring medication discontinuation