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Ipamorelin is a pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH) developed later, specifically designed to be a highly selective GHS-R1a agonist

They also display significant chromatin remodeling, forming senescence-associated heterochromatin foci (SAHF), and profound changes in gene expression [49]

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We show that KD accelerates tumour burden and shortens survival, independent of ketone metabolites