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The molecule is classified as a triple receptor agonist because it interacts with three endocrine receptors involved in metabolic regulation: the glucagon-like peptide-1 receptor (GLP-1R), the glucose-dependent insulinotropic polypeptide receptor (GIPR), and the glucagon receptor (GCGR)

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Recommended Timing and Dosing Schedule for Retatrutide Retatrutide is given as a once-weekly subcutaneous injection on a consistent chosen day, with dose escalation from a low starting dose up to 12 mg weekly as per trial protocol

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