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[DOI] [PubMed] [Google Scholar] 16.Wang X, Zuo Z, Deng J, et al

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For example, presequence proteases (conserved components of mitochondrial proteostasis), identified as Arabidopsis thaliana presequence protease 1 (AtPreP1) and presequence protease 2 (AtPreP2) in Arabidopsis and presequence protease (PITRM1) in mammals, have similar functions in mitochondrial protein quality control in both systems

LAMP2 dysregulation disrupts lysosomal homeostasis, and also impairs the activity of Cathepsin D (CTSD), a key protease for autophagosomal cargo degradation (116,117)

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