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In adults of all age who had lost weight with lifestyle intervention initially, liraglutide promoted additional weight loss in SCALE Maintenance [72]

Additionally, Dihexas small molecular weight of 750 Da allows blood-brain barrier penetration approximately 1000-fold more efficient than BDNF, which is too large to cross the BBB effectively when administered peripherally

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It was also demonstrated that lipid metabolism promoted ferroptosis in the HTGP process by regulating ACSL4/LPCAT3 levels, and that ER stress may be involved in ferroptosis through the BIP/p-EIF2/CHOP pathway

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