Epithalon is a synthetic four-amino-acid peptide (alanine-glutamic acid-aspartic acid-glycine, or AEDG) modeled on epithalamin, a compound made by the pineal gland
Conventional delivery methods lead to systemic distribution rather than targeting specific tissues or cells under oxidative stress, reducing effectiveness and increasing the required dosage as reported by Sezgin-Bayindir et al
Conventional gastroprotective drugs commonly prescribed to minimize NSAID toxicity or heal NSAID-induced ulcers include H2-receptor antagonists (cimetidine, ranitidine, famotidine), proton pump inhibitors (omeprazole, lansoprazole, esomeprazole), and misoprostol (a synthetic prostaglandin analog) (Vonkeman 2010)
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Selenometabolomics: identification of selenometabolites and specification of their biological significance by complementary use of elemental and molecular mass spectrometry
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