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The affected enzymes, ERK1/2, along with their downstream targets, including c-Fos, c-Jun, and Egr-1, are believed to play significant roles in cell growth, migration, and angiogenesis, which is the development of new blood vessels

[DOI] [PMC free article] [PubMed] [Google Scholar] 128.Zhang Y, Tan H, Daniels JD, Zandkarimi F, Liu H, Brown LM, Uchida K, OConnor OA, Stockwell BR

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Evidence-based guideline: premature ovarian insufficiency