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Figure 3c shows that surface-targeted LaccID enriches N-cadherin but not calreticulin, while surface-targeted APEX2 and HRP enrich both markers because of (1) substantial pools of APEX2 and HRP in the ER lumen because of their imperfect targeting to the cell surface, and (2) high activity of APEX2 and HRP in the ER compartment

Key Fact #1: Age-Related Factors Affecting B12 Absorption Several things change with age that make it harder to absorb B12

Before treatment, common concerns include uneven tone, dullness, tanning, and pigmentation patches

powder is more stable than reconstituted solution

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