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Retrieved May 28, 2025, from Parente, E., Colannino, G., Picconi, O., & Monastra, G

Gastrointestinal symptoms (nausea, diarrhea, constipation, abdominal pain) are most common, typically occurring during dose escalation and often improving with continued use

Less stringent oversight

Induction of liver growth by xenobiotic compounds and other stimuli

Clinical research priorities include properly designed human clinical trials with adequate sample sizes, appropriate controls, and validated outcome measures

State boards of pharmacy conduct inspections every 612 months, and sterile compound batches undergo required third-party testing