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Cell studies reported reduced 1-methylnicotinamide, altered NAD measurements and reduced lipid accumulation

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The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials

Genetic results showed that this patient was homozygous at the C677T polymorphism, which is associated with a 70% reduction in MTHFR activity