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Gene alterations of TTN (coding for Titin, 1225% of DCM), LMNA (coding for Lamina/C, 48% of DCM), DES , VLC and FLNC (coding for cytoskeletal proteins, each around 1% of DCM) significantly contribute to the DCM phenotype [105]

There are numerous well-known NAD+-dependent enzymes

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It is is also given in an epidural (spinal block) to reduce the discomfort of contractions during labor