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Importantly, several studies describing anti-ferroptotic activity are based mainly on general reductions in ROS or oxidative stress markers, while ferroptosis-specific confirmation requires assessment of key indicators such as GPX4 regulation, glutathione depletion, lipid peroxidation products, and iron-dependent rescue experiments [94, 95]

Load-bearing joints (e.g., knees and hips) are subjected to long-term mechanical stress, and their microenvironment may amplify the effects of oxidative stress and iron deposition triggered by dysbiosis

The MTT assay application to measure the viability of spermatozoa: a variety of the assay protocols

Local ethics committee approval was obtained from Van Yznc Yl University Medical Faculty Hospital before blood samples were taken (decision number:03 and date:10.02.2021)

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Gently massage in upward motions until the product is fully absorbed