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Graziano et al., 1993

The absence of safety data in these populations means that use should be avoided or approached with extreme caution and specialized medical supervision

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Others have alluded to the potential protective effect in AMD, but were among the first to show it in a large database study, says lead author Kevin Allan, MD, PhD, a resident at the Cole Eye Institute

It's a federation of 34 independent companies operating in all 50 states

The second step takes place in the gut where the metabolized estrogen is packaged up and eliminated via the stool