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The clinical extreme of chronic copper overload is Wilson disease, in which impaired biliary copper excretion produces hepatic and neurological injury a natural experiment demonstrating what happens when the copper regulatory system fails
they are regulatory molecules required for vascular integrity, tissue repair, and cellular recovery
J Immunol 143:197481, PMID: 2789253 Markovic J, Borrs C, Ortega A, Sastre J, Via J, Pallard FV (2007) Glutathione is recruited into the nucleus in early phases of cell proliferation
Not to forget its implications in brain health, skin health, and liver function