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For individuals with more metabolic resistance (pre-diabetes, metabolic syndrome, polycystic ovarian syndrome [PCOS]) GLP-1/GIP can have even greater effects on body weight, cardiovascular health, diabetes prevention, and overall improvement in health markers than GLP-1 alone

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Are compounded versions as effective as brand-name

Reductions in waist circumference and abdominal fat may occur as part of overall weight loss, particularly when accompanied by healthy lifestyle changes

Ask for the pharmacy name and whether they operate as a 503A compounding pharmacy or a 503B outsourcing facility - the distinction matters significantly given the FDA's April 2026 regulatory proposal