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In the context of chronic wounds and dysbiosis, smart nanomaterials provide novel opportunities to both disrupt biofilms and restore microbial balance, thereby promoting tissue regeneration

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Enhanced circulation is considered important for the delivery of oxygen, nutrients, and signaling molecules required during regenerative processes (19)

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Other factors that come into play when deciding on the use of PRP, particularly in the case of athletic patients, are personal preferences, the desire to adhere to the rehabilitation plan, and the cost of treatment