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3 Protein kinase A regulatory subunit- ( PRKAR1A ) is genomically inactivated in MMNST

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Under pathological stress, this system may be hijacked, leading to lactylation of pro-inflammatory or fibrotic transcripts (Zhou et al., 2024)

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The GSS then attaches glycine to it

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This can cause a variety of problems, such as muscle and joint pain, weakness, and vulnerability to infections and injuries

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Powell-Wiley TM, Poirier P, Burke LE, Despres JP, Gordon-Larsen P, Lavie CJ, et al

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