The Phase 2 trial reference point The Phase 2 retatrutide trial (Jastreboff et al., New England Journal of Medicine 2023) enrolled 338 adults across placebo and retatrutide arms at 1, 4, 8, and 12 mg weekly
So while the medications can produce remission-like states, theyre managing the condition rather than permanently curing it
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Brain iron overload, insulin resistance, and cognitive performance in obese subjects: a preliminary MRI case-control study
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