232,233 GLP-1 RAs also promote the creation of new mitochondria, which provide metabolic energy for cellular functions, aiding in both communication between cells and the signaling necessary for tissue repair
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No clinical evidence
Pilot RCTs in relapsing MS report modest EDSS improvement and lower corticosteroid need, suggesting that simultaneous enhancement of oxidative phosphorylation, NAD + cycling and membrane repair may decelerate disability accrual (84)
Studies also indicate that NDGA has antihyperglycemic effects in rat and mouse models of Type II diabetes (Reed et al