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Guidelines: the 2023 International PCOS Guideline positions GLP-1RAs as practical weight-loss tools for obese women with PCOS but emphasizes that they must be used within a framework of continuous, effective contraception throughout the treatment period, and should not be considered a routine intervention for weight or metabolic management during pregnancy ( Lactation: although preliminary data suggest extremely low milk transfer and no clear adverse signals in infants (163), the overall evidence remains insufficient

Thats something that nutritional counseling has already been shown to do

Your body needs nourishment and energy from a variety of real foods

however, LEAD-6 was open-label and the insulin glargine arm in LEAD-5 was open-label since the basal insulin dose was individually titrated

In almost every study, participants were also following diet and exercise guidance

How Do GLP-1 Antagonists Help With Weight Loss