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Treatment guidelines typically suggest adding a new agent instead of switching, particularly if the initial medication provided some benefit [87,188,189,190]

Most members see the earliest change there

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The lack of consensus on diagnostic criteria makes it difficult to know exactly how many people have MCS

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Explores how methionine metabolism supplies cysteine through the transsulfuration pathway, directly linking one-carbon metabolism to glutathione synthesis and cellular redox balance in the context of the GSH/GSSG system