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11 This illustrates that regardless of the drivers of obesity, PwO are in an established state of pathological energy homeostasis that requires intensification of treatment beyond foundational lifestyle changes, and which often requires the use of anti-obesity medications (AOMs)

Moreover, Cotadutide was demonstrated to decrease fat accumulation in the liver and retard hepatic fibrogenesis developing in high-fat diet (HFD) and HFD/CCl4 mouse models (138, 139)

1 of 29 Maximize Your Weight Loss Tirzepatide is a newer medication that combines two different classes of drugs: It works by helping the body produce more insulin and decreasing the amount of sugar produced by the liver

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