semaglutide tirzepatide comparison Efficacy of 5, 10 and 15 mg versus 2 mg in patients with type 2 diabetes: An adjusted indirect treatment Semaglutide vs. Tirzepatide: Which GLP-1

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In preclinical models using intragastric administration, researchers observed effects comparable to parenteral routes for gastrointestinal endpoints

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Rates were 0.7% among those with alcohol use disorder and 1.6% for those with opioid use disorder presumably in those with comorbid diabetes/weight issues and substance use disorder