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This is a common concern for patients considering or currently using GLP-1 receptor agonists such as semaglutide (Wegovy, Ozempic) or liraglutide (Saxenda)

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Studies looking at these effects have found increases in the order of a few percent per kg lost and sustained elevation for at least a year.1-3 Aggregated data from 5 studies (n=270) showed that blood POP concentrations rise on the order of 2-4% per kilogram of weight lost and remain elevated for at least 12 months.2 A 2021 study tracked weight loss of 100 obese patients following bariatric surgery

They already do some of this work anyway," he said