Prostate cancer (PC) is one of the most commonly and frequently diagnosed malignant solid tumours in men
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Liquid chromatography-tandem mass spectrometry was employed to quantify plasma TMAO, choline and their related metabolites, encompassing TMA, l-carnitine, betaine and dimethylglycine (DMG), which are betaine-related metabolites (Reference Wiedeman, Barr and Green14)
Extracted ion chromatograms for fragment ions were drawn for each compound in their respective channels and areas under the peak calculated and used to represent the relative abundance of the metabolites in the samples
Interpretation of (epidemiological) study results has to consider random errors of estimation (due to chance) and systematic errors or bias
Key nutrients include myo-inositol, CoQ10, active folate (5-MTHF / Quatrefolic), vitamin D, vitamin E, zinc, selenium and antioxidants