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TMAO can also be derived directly from dietary sources

The variant Val allele at the GSTP1 105 codon was associated with a significantly increased risk of surgical complications following microvacular surgical reconstruction

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In these processes, Sirtuin family proteins probably have a crucial role

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Furthermore, we assessed the impact of TMAO on autophagic flux by monitoring the number of autophagosomes and autolysosomes using a mCherry-GFP-LC3 reporter system