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The titration schedule is a framework, not a mandate

Issues generally arise only when one or both nutrients are consumed in excessive amounts for prolonged periods

Osteoporosis High blood concentrations of homocysteine may affect bone remodeling by increasing bone resorption (breakdown), decreasing bone formation, and reducing bone blood flow

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Cobalamin works with folic acid to help prevent neural tube defects

Your doctor will work with you to figure out the best duration based on your health goals and how you're responding