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Further, surface-modified (with poloxamer 188) nanoparticles PLGA co-loaded with paclitaxel/methotrexate enhanced survival rates, showed better neurological outcomes, and favorable histopathological profiles of major organs (28, 29)

doi:10.1016/bs.ctdb.2019.04.002

Lund A, Vilsboll T, Bagger JI et al (2011) The separate and combined impact of the intestinal hormones, GIP, GLP-1, and GLP-2, on glucagon secretion in type 2 diabetes

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If a person throws up often or has stomach ulcers, there may be a small risk of bleeding in the stomach or intestines

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