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However, adjusting medication doses for individual needs is a standard part of medical practice

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The selective serotonin reuptake inhibitor fluoxetine does not change rectal sensitivity and symptoms in patients with irritable bowel syndrome: a double blind, randomized, placebo-controlled study

In particular, correlations between online search volume and prescriptions were strongest for newer drugs with increasing prescription rates, as well as those with sudden shifts toward decreasing rates due to warnings or withdrawal from the market, while a sudden and rapid decoupling was noted for older GLP-1 receptor agonists that were subsequently shown to have decreasing prescription rates

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Despite decades of advances in psychopharmacology, the mortality gap between the general population and people with SMIs has not meaningfully narrowed