In a clinical study with 33 patients suffering from severe osteoarthritis 16 patients were allocated to receive 200 mg Pycnogenol per day over 3 weeks before a scheduled knee arthroplasty surgery (34)
Protective effect of black garlic extracts on tert-Butyl hydroperoxide-induced injury in hepatocytes via a c-Jun N-terminal kinase-dependent mechanism
Elsevier BV 8 , 891906 (2021)
7 There is no adequately powered, randomized, placebo-controlled human trial establishing that injected BPC-157 heals tendons, joints, or gut tissue in humans at any defined dose
Allergic reactions are uncommon but possible
Short-term treatment may provide targeted relief, however, combining antibiotics with probiotics can help reduce the harmful impact on the microbiota, while caution is suggested due to potential inflammatory responses [96102]