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In receptor assays pramlintide is the standard amylin-selective comparator and salmon calcitonin the non-selective one, and Fletcher and colleagues (J Pharmacol Exp Ther, 2021) benchmarked cagrilintide against both across 25 endpoints

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The World Anti-Doping Agency (WADA) prohibits growth hormone secretagogues and GHRH and its analogs and mimetics within its hormone-and-metabolic-modulator category, and GHRH-receptor agonists such as tesamorelin and CJC-1295 are treated as prohibited substances