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Aging 11 , 16751686 (2016)
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doi: 10.1111/1750-3841.17300 5 TomookaFKajiKNishimuraNKuboTIwaiSShibamotoAet al
Notably, ferritin light chain (FTL) and FTH1, which constitute ferritin (FN), and NCOA4, ATG5, and ATG7, which mediate iron-selective autophagy (i.e., ferritinophagy), were all highly expressed in the EMFF group, whereas the expression of E3 ubiquitin ligase (HERC2) ubiquitinated NCOA4 by ubiquitin-proteasome system decreased (Fig
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This small molecule works by selectively inhibiting nicotinamide N-methyltransferase (NNMT), an enzyme that plays a crucial role in cellular energy metabolism and fat storage regulation [1]
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