surmount-4 tirzepatide withdrawal weight regain Cardiometabolic Parameter Change by on in Adults With Obesity: A Post Hoc Analysis of the Trial Weight regain after the withdrawal

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doi: 10.1038/srep00170 85 SungJ

At 50 units (approximately 0.165 mg), the dose falls below the therapeutic threshold and would not produce meaningful glycemic or weight-loss benefits