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Consequently, FerroTACs exhibit enhanced cellular accumulation and potent degradation activity, outperforming conventional PROTACs in certain models and offering a strategic insight into designing degraders with improved pharmacokinetic profiles
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10.1186/s12943-018-0835-8 [DOI] [PMC free article] [PubMed] [Google Scholar] Fedoreyeva LI, Kireev II, Khavinson VK, Vanyushin BF (2011) Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA