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Endocr Rev
A randomized, controlled trial of 3.0 mg of liraglutide in weight management
Subjects were then divided into 3 groups based on antidiabetic medication use: control patients (no use of GLP-1 analogs or SGLT-2 inhibitors), patients on GLP-1 analogs, and patients on SGLT-2 inhibitors
Its extended duration of action comes from the same pharmacological strategy used in semaglutide and tirzepatide: a fatty acid chain that binds to albumin in the blood, slowing the drug's clearance from the body
Given the heterogeneity among GLP-1RAs in terms of pharmacokinetic profiles, therapeutic efficacy, adverse event rates, and dosing regimens, each agent should be assessed individually
That requires doing research and clinical trials to prove efficacy
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