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Triple combination formulations containing hydroquinone 4%, tretinoin and fluocinolone acetonide show increased efficiency for melasma when used under dermatologist supervision [32]

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Children with ASD commonly exhibit increased intestinal permeabilityoften referred to as leaky gutwhich allows microbial metabolites, such as short-chain fatty acids (SCFAs) and neuroactive compounds (e.g., 5-HT, GABA), to enter systemic circulation (Ullah et al., 2024)

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The serotonin transporter undergoes constitutive internalization and is primarily sorted to late endosomes and lysosomal degradation

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